Vitronectin establishes a differentiation-restrictive extracellular microenvironment that sustains myoblast proliferation across species.

Biomater. Sci., 2026, Accepted Manuscript
DOI: 10.1039/D6BM00313C, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Tomoka Katayama, Anmi Matsumoto, Yoka Takazawa, Momoka Hashino, Minoru Kaito, Yuta Chigi, Daiji Okamura
The extracellular matrix (ECM) critically regulates cell fate decisions, yet matrix components that actively impose differentiation-restrictive states remain insufficiently defined from a biomaterials perspective. Here, we identify vitronectin (VN), a...
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