Designed Gramicidin Inspired Stabilized Peptide-based Therapeutics to Potentiate Immunotherapy Against Aggressive Kidney Cancer

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Biomater. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5BM00109A, Paper
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Rituparna Sinha Roy, Argha Mario Mallick, Ananya Chatterjee, Arun Bahadur Gurung, Prithviraj Uttarasili, Archana Tripathi, Monjuri Hembram, Anand Srivastava
This study reports engineered protease-stable, gramicidin-inspired, peptide-based proton transporter LD8∆, having alternate L- and D- amino acid residues to treat highly chemoresistant, radioresistant, immunosuppressive metastatic renal cell carcinomas (RCCs) cell...
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